Heat a Dutch oven over medium-high heat. Cook and stir ground beef, onion, and garlic until beef is browned and crumbly and onion is translucent, 5 to 7 minutes. Drain and discard excess grease.
Stir in tomato sauce, diced tomatoes, water, chili powder, oregano, and black pepper. Bring to a boil. Cover, reduce heat, and let simmer, stirring often, for about 30 minutes.
Break spaghetti into thirds and add to the pot; cover and simmer, stirring often, until pasta is tender, about 20 minutes. Serve topped with Parmesan cheese.
Per Serving: 323 calories; protein 22.8g; carbohydrates 34.5g; fat 11g; cholesterol 55.6mg; sodium 567.6mg.
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